Persistence of Antibody Responses to Haemophilus influenzae Type b Polysaccharide Conjugate Vaccine in Children with Vertically Acquired Human Immunodeficiency Virus Infection

Not only was the initial antibody response to Hib conjugate vaccine decreased in children with HIV infection and AIDS but also 1 year later only 57% of the initial responders had persisting titers above the level associated with long term protection. The need for reimmunization of children with HIV infection against Hib requires further evaluation.