Treatment of Renal Allograft Polyoma BK Virus Infection with Leflunomide

2006225 citationsJournal Article

Authors

Michelle A. Josephson · University of Chicago

Daniel L. Gillen · University of Chicago

Basit Javaid · University of Chicago

Pradeep V. Kadambi · University of Chicago

S. Meehan · University of Chicago

Preston Foster · CHRISTUS Transplant Institute

Robert C. Harland

Abstract

Leflunomide inhibits Polyoma virus replication in vitro and closely monitored leflunomide therapy with specifically targeted blood levels appears to be a safe and effective treatment for Polyoma BK nephropathy.

Topics & Keywords

Polyomavirus and related diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Transplantation

Volume 81, Issue 5, pp. 704-710

DOI: 10.1097/01.tp.0000181149.76113.50

Field-Weighted Citation Impact: 9.31