Fresh Whole Blood versus Reconstituted Blood for Pump Priming in Heart Surgery in Infants

2004181 citationsJournal Article

Authors

Steven S. Mou · Children's Medical Center

Brett P. Giroir · Children's Medical Center

Erica Molitor-Kirsch · Children's Medical Center

Steven Leonard · The University of Texas Southwestern Medical Center

Hisashi Nikaidoh · The University of Texas Southwestern Medical Center

Frank Nizzi · Carter BloodCare

Deborah A. Town

Abstract

The use of fresh whole blood for cardiopulmonary bypass priming has no advantage over the use of a combination of packed red cells and fresh-frozen plasma during surgery for congenital heart disease. Moreover, circuit priming with fresh whole blood is associated with an increased length of stay in the intensive care unit and increased perioperative fluid overload.

Topics & Keywords

Cardiac and Coronary Surgery Techniques Mechanical Circulatory Support Devices Cardiac Arrest and Resuscitation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 351, Issue 16, pp. 1635-1644

DOI: 10.1056/nejmoa041065

Field-Weighted Citation Impact: 8.62