α<sub>1</sub>‐Acid glycoprotein fucosylation as a marker of carcinoma progression and prognosis

2004108 citationsJournal Article

Authors

Shinji Hashimoto · Gunma University

Takayuki Asao · Gunma University

Junko Takahashi · JIMRO (Japan)

Yuko Yagihashi · JIMRO (Japan)

Toyo Nishimura · Otsuka (Japan)

Abby R. Saniabadi · JIMRO (Japan)

Dennis C.W. Poland · Diakonessenhuis hospital

Abstract

Patients with advanced malignancies who had AGP glycoforms that contained highly fucosylated triantennary and tetraantennary sugar chains for long periods after surgery were likely to have a poor prognosis. However, patients who had AGP glycoforms without such changes were expected to have a good prognosis.

Topics & Keywords

Glycosylation and Glycoproteins Research Galectins and Cancer Biology Monoclonal and Polyclonal Antibodies Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Cancer

Volume 101, Issue 12, pp. 2825-2836

DOI: 10.1002/cncr.20713

Field-Weighted Citation Impact: 1.40