Role of Reactive Oxygen Species in Hypertension Produced by Reduced Uterine Perfusion in Pregnant Rats

2008133 citationsJournal Articlebronze Open Access

Authors

Mona Sedeek · University of Mississippi Medical Center

Jeffrey S. Gilbert · University of Mississippi Medical Center

Birdie LaMarca · University of Mississippi Medical Center

Myssara Sholook · University of Mississippi Medical Center

Danielle L. Chandler · University of Mississippi Medical Center

Y. Wang · Louisiana State University Health Sciences Center Shreveport

Joey P. Granger

Abstract

The results of this study indicate that placental ischemia decreases innate antioxidant activity resulting in elevated oxidative stress which appears to play a role in mediating hypertension associated with chronic RUPP in pregnant rats.

Topics & Keywords

Pregnancy and preeclampsia studies Birth, Development, and Health Maternal and fetal healthcare

Publication Details

Published in: American Journal of Hypertension

Volume 21, Issue 10, pp. 1152-1156

DOI: 10.1038/ajh.2008.239

Field-Weighted Citation Impact: 7.00

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Role of Reactive Oxygen Species in Hypertension Produced by Reduced Uterine Perfusion in Pregnant Rats

Authors

Abstract

Topics & Keywords

Publication Details