Bisphenol A Exposure during Adulthood Causes Augmentation of Follicular Atresia and Luteal Regression by Decreasing 17β-Estradiol Synthesis via Downregulation of Aromatase in Rat Ovary

2013132 citationsJournal Articlediamond Open Access

Authors

Seung Gee Lee · Mitochondria Research and Medicine Society

Ji Young Kim · Mitochondria Research and Medicine Society

Jin‐Yong Chung · Dong-A University

Yoon Jae Kim · Mitochondria Research and Medicine Society

Ji‐Eun Park · Mitochondria Research and Medicine Society

Seunghoon Oh · Dankook University

Yong‐Dal Yoon

Abstract

BPA exposure during adulthood can disturb the maintenance of normal ovarian functions by reducing E2. The steroidogenic proteins StAR and P450arom appear to be targeted by BPA.

Topics & Keywords

Effects and risks of endocrine disrupting chemicals

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Environmental Health Perspectives

Volume 121, Issue 6, pp. 663-669

DOI: 10.1289/ehp.1205823

Field-Weighted Citation Impact: 6.23