Localized Conjunctival Amyloidosis: Case Reports and Review of Literature

Two men in their 20s had flat, stable, pink, well-vascularized conjunctival lesions found unexpectedly which on biopsy proved to be primary localized amyloidosis. The diagnosis was made possible by the absence of systemic manifestations or antecedent ocular disease, the presence of diffuse homogeneous connective tissue deposits and characteristic histochemical staining properties. The cases were remarkable for their color, texture, location, and presentation and suggest that a high index of suspicion, if not an alacrity to biopsy, is needed for the diagnosis of primary localized amyloid to be made.