Multipotent Mesenchymal Stem Cells with Immunosuppressive Activity Can Be Easily Isolated from Dental Pulp

2005601 citationsJournal Article

Authors

Laura Pierdomenico · University of Bologna

Laura Bonsi · University of Bologna

Mario Calvitti

Damiano Rondelli

Mario Arpinati · University of Bologna

Gabriella Chirumbolo · University of Bologna

Ennio Becchetti

Cosetta Marchionni · University of Bologna

Abstract

Dental pulp is an easily accessible and efficient source of MSCs, with different kinetics and differentiation potentialities from MSCs as isolated from the bone marrow. The rapid proliferative capacity together with the immunoregulatory characteristics of DP-MSCs may prompt future studies aimed at using these cells in the treatment or prevention of T-cell alloreactivity in hematopoietic or solid organ allogeneic transplantation.

Topics & Keywords

Mesenchymal stem cell research Periodontal Regeneration and Treatments Oral health in cancer treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Transplantation

Volume 80, Issue 6, pp. 836-842

DOI: 10.1097/01.tp.0000173794.72151.88

Field-Weighted Citation Impact: 6.84