Increased methylation at differentially methylated region of GNASin infants born to gestational diabetes

201445 citationsJournal Articlegold Open Access

Authors

Danqing Chen · Women's Hospital, School of Medicine, Zhejiang University

Aiping Zhang · Shanghai Jiao Tong University

Min Fang · Shaoxing City Women and Children Hospital

Rong Fang · Huzhou Women and Children's Hospital

Jia-mei Ge · First Hospital of Jiaxing

Yuan Jiang

Hong Zhang · Fudan University

Abstract

We concluded maternal GDM-induced hypermethylation at GNAS DMR and this condition may be among the mechanisms associating maternal GDM with increased risk of metabolic diseases in later life of offspring.

Topics & Keywords

Gestational Diabetes Research and Management Epigenetics and DNA Methylation Pregnancy and preeclampsia studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMC Medical Genetics

Volume 15, Issue 1, pp. 108-108

DOI: 10.1186/s12881-014-0108-3

Field-Weighted Citation Impact: 4.76