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Large-eddy simulations of a subsonic three-dimensional cavity flow with self-sustaining oscillations are carried out for a Reynolds number based on the length of the cavity equal to $7\,{\times}\,10^6$ . Meticulous comparisons with available experimental data corresponding to the same configuration demonstrate a high level of accuracy. Special attention is paid to the mixing layer that develops over the cavity and two different zones are identified. The first one is dominated by Kelvin–Helmholtz instability, and the linear as well as quadratic energy transfers leading to the filling of velocity spectra are described. The Kelvin–Helmholtz instability also appears to be forced near the origin of the layer, and it is postulated that the small recirculation bubble located in this area is responsible for the forcing. Downstream of the first zone and up to the vicinity of the aft wall, the layer behaves very similarly to a free mixing layer by exhibiting a linear spreading. An influence of the recirculating flow inside the cavity upon the growth of the layer is nevertheless observed at downstream stations. Analysis of the pressure on the floor of the cavity reveals that the self-sustaining oscillation-related pressure modes (Rossiter modes) are independent of their spanwise location inside the cavity. On the contrary, Rossiter modes exhibit streamwise modulations and it is demonstrated that a very simple two-wave model is able to reproduce the spatial shape of the modes. Nonlinear interactions between Rossiter modes are encountered, as well as nonlinear interactions with low-frequency components. A joint time–frequency analysis shows a temporal modulation of the Rossiter mode levels at similar low frequencies, resulting in a special form of intermittency with competitive energy exchanges between modes.