Interleukin 15: biology and relevance to human disease

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Authors

Todd A. Fehniger · Cancer Genetics (United States)

Michael A. Caligiuri · Cancer Genetics (United States)

Abstract

Since the cloning of interleukin (IL)-15 six years ago, there have been numerous studies examining the molecular and cellular biology of this cytokine. IL-15 and IL-2 have similar biologic properties in vitro, consistent with their shared receptor (R) signaling components (IL-2/15Rβγc). However,

Topics & Keywords

Immune Cell Function and Interaction T-cell and Retrovirus Studies Whipple's Disease and Interleukins

Publication Details

Published in: Blood

Volume 97, Issue 1, pp. 14-32

DOI: 10.1182/blood.v97.1.14

Field-Weighted Citation Impact: 16.23

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Interleukin 15: biology and relevance to human disease

Authors

Abstract

Topics & Keywords

Publication Details