Efficacy and Safety of Oral Lacosamide as Adjunctive Therapy in Adults with Partial‐Onset Seizures

2007478 citationsJournal Article

Authors

Elinor Ben‐Menachem · University of Gothenburg

Victor Biton · Arkansas Cardiology

Dalius Jatužis · Vilnius University

Bassel Abou‐Khalil · Vanderbilt University

Pamela Doty

G. David Rudd

Abstract

In this trial, adjunctive lacosamide significantly reduced seizure frequency in patients with uncontrolled partial-onset seizures. Along with favorable pharmacokinetic and tolerability profiles, these results support further development of lacosamide as an AED.

Topics & Keywords

Epilepsy research and treatment Pharmacological Effects and Toxicity Studies Neuroscience and Neuropharmacology Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Epilepsia

Volume 48, Issue 7, pp. 1308-1317

DOI: 10.1111/j.1528-1167.2007.01188.x

Field-Weighted Citation Impact: 13.41