Genistein induces radioprotection by hematopoietic stem cell quiescence

200885 citationsJournal Article

Authors

Thomas A. Davis · Naval Medical Research Command

Stephen R. Zins · Naval Medical Research Command

Michael R. Landauer · Uniformed Services University of the Health Sciences

Abstract

Pretreatment with genistein provides in vivo protection from acute myelotoxicity through extended quiescence followed by reduced senescence of marrow repopulating LSK(+).

Topics & Keywords

Effects of Radiation Exposure DNA Repair Mechanisms Carcinogens and Genotoxicity Assessment

Publication Details

Published in: International Journal of Radiation Biology

Volume 84, Issue 9, pp. 713-726

DOI: 10.1080/09553000802317778

Field-Weighted Citation Impact: 2.72

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Genistein induces radioprotection by hematopoietic stem cell quiescence

Authors

Abstract

Topics & Keywords

Publication Details