Loss of myocardial protection after preconditioning correlates with the time course of glycogen recovery within the preconditioned segment.

1993201 citationsJournal Article

Authors

Christopher L. Wolfe · University of California, San Francisco

Richard E. Sievers · University of California, San Francisco

Frank L.J. Visseren · University of California, San Francisco

Thomas J. Donnelly · University of California, San Francisco

Abstract

Glycogen depletion and the attenuation of intracellular acidosis during ischemia appear to be important factors in delaying irreversible injury and reducing infarct size in this animal model of myocardial preconditioning.

Topics & Keywords

Cardiac Ischemia and Reperfusion Anesthesia and Neurotoxicity Research Cardiac Arrest and Resuscitation

UN Sustainable Development Goals

Affordable and clean energy

Publication Details

Published in: Circulation

Volume 87, Issue 3, pp. 881-892

DOI: 10.1161/01.cir.87.3.881

Field-Weighted Citation Impact: 12.02