Optimised empiric triple and concomitant therapy for<i>Helicobacter pylori</i>eradication in clinical practice: the OPTRICON study

Empiric OPT-CON therapy achieved significantly higher cure rates (>90%) compared to OPT-TRI therapy. Addition of metronidazole to OPT-TRI therapy increased eradication rates by 10%, resulting in more mild adverse effects, but without impairing compliance with therapy.