Improvement of Autoimmune Hepatitis During Pregnancy Followed by Flare-Up After Delivery

2002174 citationsJournal Article

Authors

Johan Fevery · Universitair Ziekenhuis Leuven

Abstract

Pregnancy induces a state of immune tolerance with improvement of the liver tests in AIH. This could result from a transition of TH1 to TH2 predominance during pregnancy. A flare-up often occurs after delivery. Preemptive increase of the immunosuppressive therapy is therefore advocated consecutive to delivery. Azathioprine use seems to be safe during pregnancy.

Topics & Keywords

Liver Diseases and Immunity Liver Disease Diagnosis and Treatment Hepatitis Viruses Studies and Epidemiology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The American Journal of Gastroenterology

Volume 97, Issue 12, pp. 3160-3165

DOI: 10.1111/j.1572-0241.2002.07124.x

Field-Weighted Citation Impact: 1.79