DNA methylation age of human tissues and cell types

20137,051 citationsJournal Articlegold Open Access

Authors

Steve Horvath · University of California, Los Angeles

Abstract

I propose that DNA methylation age measures the cumulative effect of an epigenetic maintenance system. This novel epigenetic clock can be used to address a host of questions in developmental biology, cancer and aging research.

Topics & Keywords

Epigenetics and DNA Methylation Genomics and Chromatin Dynamics RNA modifications and cancer

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Genome biology

Volume 14, Issue 10, pp. R115-R115

DOI: 10.1186/gb-2013-14-10-r115

Field-Weighted Citation Impact: 71.30