[<sup>18</sup>F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease

2013603 citationsJournal Article

Authors

Chun‐Fang Xia · Siemens Healthcare (United States)

Janna Arteaga · Siemens Healthcare (United States)

Gang Chen · Siemens Healthcare (United States)

Umesh Gangadharmath · Siemens Healthcare (United States)

Luis F. Gomez · Siemens Healthcare (United States)

Dhanalakshmi Kasi · Siemens Healthcare (United States)

Chung Lam

Abstract

[(18)F]T807 demonstrates high affinity and selectivity to PHF-tau as well as favorable in vivo properties, making this a promising candidate as an imaging agent for AD.

Topics & Keywords

Alzheimer's disease research and treatments Prion Diseases and Protein Misfolding Parkinson's Disease Mechanisms and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Alzheimer s & Dementia

Volume 9, Issue 6, pp. 666-676

DOI: 10.1016/j.jalz.2012.11.008

Field-Weighted Citation Impact: 26.08