Memantine Monotherapy for Alzheimer’s Disease: A Systematic Review and Meta-Analysis

2015270 citationsReviewgold Open Access

Authors

Shinji Matsunaga · Fujita Health University

Abstract

Memantine monotherapy improved cognition, behavior, activities of daily living, global function, and stage of dementia and was well-tolerated by AD patients. However, the effect size in terms of efficacy outcomes was small and thus there is limited evidence of clinical benefit.

Topics & Keywords

Dementia and Cognitive Impairment Research Blood Pressure and Hypertension Studies Pharmaceutical Practices and Patient Outcomes

Publication Details

Published in: PLoS ONE

Volume 10, Issue 4, pp. e0123289-e0123289

DOI: 10.1371/journal.pone.0123289

Field-Weighted Citation Impact: 14.10

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Memantine Monotherapy for Alzheimer’s Disease: A Systematic Review and Meta-Analysis

Authors

Abstract

Topics & Keywords

Publication Details