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ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructural and Functional Aspects of Metal Sites in BiologyRichard H. Holm, Pierre Kennepohl, and Edward I. SolomonView Author Information Departments of Chemistry, Harvard University, Cambridge, Massachusetts 02138, and Stanford University, Stanford, California 94305 Cite this: Chem. Rev. 1996, 96, 7, 2239–2314Publication Date (Web):November 7, 1996Publication History Received10 June 1996Revised3 September 1996Published online7 November 1996Published inissue 1 January 1996https://pubs.acs.org/doi/10.1021/cr9500390https://doi.org/10.1021/cr9500390research-articleACS PublicationsCopyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views16245Altmetric-Citations2150LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Copper,Iron,Ligands,Metals,Peptides and proteins Get e-Alerts