Anti-C1q antibodies in systemic lupus erythematosus

2014110 citationsJournal Articlegreen Open Access

Authors

Ana‐Maria Orbai · Johns Hopkins University

Lennart Truedsson · Lund University

Gunnar Sturfelt · Skåne University Hospital

Ola Nived · Skåne University Hospital

Hong Fang · Johns Hopkins University

Graciela S. Alarcón · University of Alabama at Birmingham

Caroline Gordon ·

Abstract

Anti-C1q was more common in patients with SLE and those of Asian race/ethnicity. We confirmed a significant association of anti-C1q with renal involvement, independent of demographics and other serologies. Anti-C1q in combination with anti-dsDNA and low complement was the strongest serological association with renal involvement. These data support the usefulness of anti-C1q in SLE, especially in lupus nephritis.

Topics & Keywords

Systemic Lupus Erythematosus Research Complement system in diseases Renal Diseases and Glomerulopathies

Publication Details

Published in: Lupus

Volume 24, Issue 1, pp. 42-49

DOI: 10.1177/0961203314547791

Field-Weighted Citation Impact: 9.95

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Anti-C1q antibodies in systemic lupus erythematosus

Authors

Abstract

Topics & Keywords

Publication Details