Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

ADVERTISEMENT RETURN TO ISSUEPerspectiveNEXTSynopsis of Some Recent Tactical Application of Bioisosteres in Drug DesignNicholas A. Meanwell*View Author Information Department of Medicinal Chemistry, Bristol-Myers Squibb Pharmaceutical Research and Development, 5 Research Parkway, Wallingford, Connecticut 06492, United StatesContact information. Phone: 203-677-6679. Fax: 203-677-7884. E-mail: [email protected]Cite this: J. Med. Chem. 2011, 54, 8, 2529–2591Publication Date (Web):March 17, 2011Publication History Received20 October 2010Published online17 March 2011Published inissue 28 April 2011https://pubs.acs.org/doi/10.1021/jm1013693https://doi.org/10.1021/jm1013693review-articleACS PublicationsCopyright © 2011 American Chemical SocietyRequest reuse permissionsArticle Views91020Altmetric-Citations2203LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Antagonists,Heterocyclic compounds,Inhibitors,Molecules,Peptides and proteins Get e-Alerts