Renal Syndromes Associated with Nonsteroidal Antiinflammatory Drugs

NONSTEROIDAL antiinflammatory drugs (NSAIDs) have become an integral part of the therapy of rheumatologic disorders.1 The number of new agents available on the market has more than tripled in the past five to seven years,2 and several pharmaceutical companies have recently introduced more potent, longer-acting agents in expectation of a share of a predicted $1-billion market in 1984.3 NSAIDs are now the most widely prescribed of all drugs when grouped by generic categories, and this does not include aspirin, which is the most commonly used of all drugs and the prototype of NSAIDs.4 Data from the Arthritis Foundation indicate that . . .