Angiotensin II Stimulates the Release of Interleukin-6 and Interleukin-8 From Cultured Human Adipocytes by Activation of NF-κB

2004127 citationsJournal Article

Authors

Thomas Skurk · Weihenstephan-Triesdorf University of Applied Sciences

Vanessa van Harmelen · Weihenstephan-Triesdorf University of Applied Sciences

Hans Hauner · Weihenstephan-Triesdorf University of Applied Sciences

Abstract

Ang II stimulates IL-6 and IL-8 production and release from human adipocytes by a NF-kappaB-dependent pathway. This proinflammatory action of Ang II seems to be mediated by the AT1 and less by the AT2 receptor subtype.

Topics & Keywords

Adipokines, Inflammation, and Metabolic Diseases Adipose Tissue and Metabolism Cytokine Signaling Pathways and Interactions

Publication Details

Published in: Arteriosclerosis Thrombosis and Vascular Biology

Volume 24, Issue 7, pp. 1199-1203

DOI: 10.1161/01.atv.0000131266.38312.2e

Field-Weighted Citation Impact: 4.64

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Angiotensin II Stimulates the Release of Interleukin-6 and Interleukin-8 From Cultured Human Adipocytes by Activation of NF-κB

Authors

Abstract

Topics & Keywords

Publication Details