Preparation of 7‐aminoquinolines as candidate antiparasitic agents

19824 citationsJournal Article

Authors

A. Markovac · Ash Stevens (United States)

Geng‐Shuen Wu · Ash Stevens (United States)

M. P. LAMONTAGNE · Ash Stevens (United States)

Peter Blumbergs · Ash Stevens (United States)

Ao Meng‐Sheng · Ash Stevens (United States)

Abstract

Abstract A series of ten 7‐quinolinediamines were prepared and evaluated for potential antiparasitic activity against P. berghei, P. cynomolgi, L. donovani and T. rhodesiense. Compounds 1d and 8 showed activity being slightly effective against L. donovani in hamsters.

Topics & Keywords

Synthesis and Biological Evaluation Phenothiazines and Benzothiazines Synthesis and Activities

Publication Details

Published in: Journal of Heterocyclic Chemistry

Volume 19, Issue 4, pp. 829-832

DOI: 10.1002/jhet.5570190424

Field-Weighted Citation Impact: 0.56

Command Palette

Preparation of 7‐aminoquinolines as candidate antiparasitic agents

Authors

Abstract

Topics & Keywords

Publication Details