Concentrations of protease inhibitors in cord blood after in utero exposure

200259 citationsJournal Article

Authors

Mark Mirochnick · Boston University

Alex Dorenbaum · BCS — The Chartered Institute for IT

Diane Holland · BCS — The Chartered Institute for IT

BETHANN CUNNINGHAM-SCHRADER · BCS — The Chartered Institute for IT

Colleen Cunningham · BCS — The Chartered Institute for IT

Richard D. Gelber · BCS — The Chartered Institute for IT

Lynne Mofenson

Abstract

Low protease inhibitor concentrations in the fetus decrease the likelihood of teratogenic and toxic effects of these drugs but could fail to provide protection from transplacental or intrapartum transmission of HIV-1.

Topics & Keywords

HIV/AIDS Research and Interventions HIV/AIDS drug development and treatment Pregnancy and Medication Impact

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Pediatric Infectious Disease Journal

Volume 21, Issue 9, pp. 835-838

DOI: 10.1097/00006454-200209000-00010

Field-Weighted Citation Impact: 2.86