p38 Mediates Mechanical Allodynia in a Mouse Model of Type 2 Diabetes

201062 citationsJournal Articlegold Open Access

Authors

Hsinlin T. Cheng · University of Michigan–Ann Arbor

Jacqueline R. Dauch · University of Michigan–Ann Arbor

Sang Su Oh · University of Michigan–Ann Arbor

John M. Hayes · University of Michigan–Ann Arbor

Yu Hong · University of Michigan–Ann Arbor

Eva L. Feldman · University of Michigan–Ann Arbor

Abstract

Our findings suggest that NGF activated-p38 phosphorylation mediates mechanical allodynia in the db/db mouse by upregulation of multiple inflammatory mediators in LDRG.

Topics & Keywords

Pain Mechanisms and Treatments Myofascial pain diagnosis and treatment Biochemical effects in animals

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Molecular Pain

Volume 6, pp. 28-28

DOI: 10.1186/1744-8069-6-28

Field-Weighted Citation Impact: 3.59