Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist

1998972 citationsJournal Article

Authors

Barry Bresnihan

Jos� Maria Alvaro-Gracia · Hospital Universitario de La Princesa

Mark Cobby · Frenchay Hospital

Michael Doherty · Nottingham City Hospital

Z Domljan · University Hospital Centre Zagreb

Paul Emery · Leeds General Infirmary

George Nuki · University of Edinburgh

Abstract

This study confirmed both the efficacy and the safety of IL-1Ra in a large cohort of patients with active and severe RA. IL-1Ra is the first biologic agent to demonstrate a beneficial effect on the rate of joint erosion.

Topics & Keywords

Rheumatoid Arthritis Research and Therapies Autoimmune and Inflammatory Disorders Research Systemic Lupus Erythematosus Research

UN Sustainable Development Goals

Life below water

Publication Details

Published in: Arthritis & Rheumatism

Volume 41, Issue 12, pp. 2196-2204

DOI: 10.1002/1529-0131(199812)41:12<2196::aid-art15>3.0.co;2-2

Field-Weighted Citation Impact: 37.55