Intra-Arterial Nicardipine Infusion Improves CT Perfusion–Measured Cerebral Blood Flow in Patients with Subarachnoid Hemorrhage–Induced Vasospasm

200850 citationsJournal Articlehybrid Open Access

Authors

Raul G. Nogueira · Harvard University

Michael H. Lev · Harvard University

Luca Roccatagliata · Harvard University

Joshua A Hirsch · Harvard University

R.G. Gonzalez · Harvard University

Christopher S. Ogilvy · Harvard University

Elkan F. Halpern · Harvard University

Abstract

IA nicardipine improves CBF and MTT in ischemic regions in patients with aSAH-induced vasospasm. Our data provide a tissue-level complement to the favorable effects of IA nicardipine reported on prior angiographic studies. CTP may provide a surrogate marker for monitoring the success of treatment strategies in patients with aSAH-induced vasospasm.

Topics & Keywords

Intracranial Aneurysms: Treatment and Complications Traumatic Brain Injury and Neurovascular Disturbances Acute Ischemic Stroke Management

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: American Journal of Neuroradiology

Volume 30, Issue 1, pp. 160-164

DOI: 10.3174/ajnr.a1275

Field-Weighted Citation Impact: 3.43