Circumscribed numerical deficit of dorsal raphe neurons in mood disorders

2002103 citationsJournal Article

Authors

B. Baumann · Evangelische Kliniken Gelsenkirchen

Hendrik Bielau · Luther University

Dieter Krell · Martin Luther University Halle-Wittenberg

M.W. Agelink · Evangelische Kliniken Gelsenkirchen

S. Diekmann · Luther University

C. Wurthmann · Luther University

Kurt Trübner ·

Abstract

Results indicate that patients with primary mood disorders have a circumscribed numerical neuronal deficiency in the dorsal raphe. This structural deviation may contribute to impaired serotonergic innervation of brain regions which are involved in the pathology of mood disorders.

Topics & Keywords

Neurotransmitter Receptor Influence on Behavior Neuroscience and Neuropharmacology Research Neurological disorders and treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Psychological Medicine

Volume 32, Issue 1, pp. 93-103

DOI: 10.1017/s0033291701004822

Field-Weighted Citation Impact: 1.07