Homozygosity for the patatin‐like phospholipase‐3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease†

2010645 citationsJournal Articlebronze Open Access

Authors

Luca Valenti · Istituti di Ricovero e Cura a Carattere Scientifico

Ahmad Al‐Serri · Newcastle University

Ann K. Daly · Newcastle University

E. Galmozzi · Istituti di Ricovero e Cura a Carattere Scientifico

Raffaela Rametta · Istituti di Ricovero e Cura a Carattere Scientifico

Paola Dongiovanni · Istituti di Ricovero e Cura a Carattere Scientifico

Valério Nobili

Abstract

In patients with NAFLD, adiponutrin rs738409 C-->G genotype, encoding for I148M, is associated with the severity of steatosis and fibrosis and the presence of nonalcoholic steatohepatitis.

Topics & Keywords

Liver Disease Diagnosis and Treatment Endoplasmic Reticulum Stress and Disease Diet, Metabolism, and Disease

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Hepatology

Volume 51, Issue 4, pp. 1209-1217

DOI: 10.1002/hep.23622

Field-Weighted Citation Impact: 29.03