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Genetic Modifiers of Lung Disease in Cystic Fibrosis

2005494 citationsJournal Articlebronze Open Access

Authors

Mitchell L. Drumm · Case Western Reserve University

Michael W. Konstan · Case Western Reserve University

Mark Schluchter · Case Western Reserve University

Allison Handler

Maimoona A. Zariwala

David C. Fargo · University of North Carolina at Chapel Hill

Abstract

Genetic variation in the 5' end of TGFbeta1 or a nearby upstream region modifies disease severity in cystic fibrosis.

Topics & Keywords

Cystic Fibrosis Research Advances Neonatal Respiratory Health Research Childhood Cancer Survivors' Quality of Life

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 353, Issue 14, pp. 1443-1453

DOI: 10.1056/nejmoa051469

Field-Weighted Citation Impact: 29.56

Genetic Modifiers of Lung Disease in Cystic Fibrosis | Researchclopedia

· University of North Carolina at Chapel Hill

John M. Dunn · Case Western Reserve University

Rebecca Darrah · Case Western Reserve University

Ruslan Dorfman · Hospital for Sick Children

Andrew J. Sandford · University of British Columbia

Mary Corey · Hospital for Sick Children

Julian Zielenski · Hospital for Sick Children

Peter R. Durie · Hospital for Sick Children

Katrina A.B. Goddard · Case Western Reserve University

James R. Yankaskas

Michael R. Knowles