Recombinant structures expand and contract inter and intragenic diversification at the KIR locus

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Authors

Chul-Woo Pyo · Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa

Ruihan Wang · Fred Hutch Cancer Center

Quyen Vu · Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa

Nezih Cereb · Histogen (United States)

Soo Young Yang · Histogen (United States)

Fuh Mei Duh · Frederick National Laboratory for Cancer Research

Abstract

These new structures suggest a number of specific recombinant events during the course of KIR evolution, and add to an expanding diversity of potential new KIR haplotypes derived from gene duplication, deletion, and hybridization.

Topics & Keywords

Immune Cell Function and Interaction T-cell and B-cell Immunology Immune Response and Inflammation

Publication Details

Published in: BMC Genomics

Volume 14, Issue 1, pp. 89-89

DOI: 10.1186/1471-2164-14-89

Field-Weighted Citation Impact: 3.08

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Recombinant structures expand and contract inter and intragenic diversification at the KIR locus

Authors

Abstract

Topics & Keywords

Publication Details