Antibodies Against Deamidated Gliadin as New and Accurate Biomarkers of Childhood Coeliac Disease

200969 citationsJournal Article

Authors

Christian Prause · University Hospital Leipzig

M RITTER · University Hospital Leipzig

Christian Probst · Euroimmun Medizinische Labordiagnostika (Germany)

Cornelia Daehnrich · Euroimmun Medizinische Labordiagnostika (Germany)

Wolfgang Schlumberger · Euroimmun Medizinische Labordiagnostika (Germany)

Lars Komorowski · Euroimmun Medizinische Labordiagnostika (Germany)

Ruediger Lieske

Abstract

The new IgA and IgG-anti-dGli tests outperform conventional anti-nGli assays. The validity of IgG-anti-dGli cannot be distinguished from IgA-anti-tTG. It should be studied prospectively whether antibody assays could replace biopsy in diagnosis of CD in a substantial segment of children.

Topics & Keywords

Celiac Disease Research and Management Microscopic Colitis Eosinophilic Esophagitis

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Pediatric Gastroenterology and Nutrition

Volume 49, Issue 1, pp. 52-58

DOI: 10.1097/mpg.0b013e318195dae3

Field-Weighted Citation Impact: 5.65