A Pilot Trial of Prazosin, an Alpha‐1 Adrenergic Antagonist, for Comorbid Alcohol Dependence and Posttraumatic Stress Disorder

201592 citationsJournal Article

Authors

Tracy L. Simpson · VA Puget Sound Health Care System

Carol A. Malte · Center for Excellence in Education

Bergetta Dietel · Center for Excellence in Education

Dana Tell · VA Puget Sound Health Care System

Ian Pocock · Seattle Institute for Biomedical and Clinical Research

Robert Lyons · Seattle Institute for Biomedical and Clinical Research

Dana Varon

Abstract

Consistent with the extant research evaluating medications for comorbid PTSD/AD, the current evaluation of prazosin also found decreased alcohol consumption but no medication effect on PTSD symptomatology.

Topics & Keywords

Posttraumatic Stress Disorder Research Child Abuse and Trauma Suicide and Self-Harm Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Alcoholism Clinical and Experimental Research

Volume 39, Issue 5, pp. 808-817

DOI: 10.1111/acer.12703

Field-Weighted Citation Impact: 15.38