A Convenient Procedure for Esterification of Carboxylic Acids

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Abstract

Abstract A variety of carboxylic acids including simple acids, sterically hindered acids, thermally unstable acids and N-protected amino acids react with alkyl halides in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) in benzene to give esters in good yields. The reaction is simple, affording a general method for esterification of carboxylic acids.

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Inorganic and Organometallic Chemistry Chemical Synthesis and Reactions Chemical Synthesis and Analysis

Publication Details

Published in: Bulletin of the Chemical Society of Japan

Volume 51, Issue 8, pp. 2401-2404

DOI: 10.1246/bcsj.51.2401

Field-Weighted Citation Impact: 5.46

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A Convenient Procedure for Esterification of Carboxylic Acids

Authors

Abstract

Topics & Keywords

Publication Details