Sustained focal antitumor activity of bevacizumab in recurrent glioblastoma

201426 citationsJournal Article

Authors

Oliver Bähr · Goethe University Frankfurt

Patrick N. Harter · Goethe University Frankfurt

Lutz Weise · Goethe University Frankfurt

Se-Jong You · Goethe University Frankfurt

Michel Mittelbronn · Goethe University Frankfurt

Michael Ronellenfitsch · Goethe University Frankfurt

Johannes Rieger

Abstract

BEV-induced double-positive MRI lesions are a predictive imaging marker associated with a substantial survival benefit and with improved local control in patients with recurrent glioblastoma. Our data suggest that these lesions are the result of a sustained focal antitumor activity of BEV.

Topics & Keywords

Glioma Diagnosis and Treatment Nanoplatforms for cancer theranostics Cancer, Hypoxia, and Metabolism

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Neurology

Volume 83, Issue 3, pp. 227-234

DOI: 10.1212/wnl.0000000000000594

Field-Weighted Citation Impact: 2.62