Fatal encephalitis/encephalopathy in primary human herpesvirus-6 infection.

1992159 citationsJournal Articlebronze Open Access

Authors

Yukio Asano · Fujita Health University

Tetsushi Yoshikawa · Fujita Health University

Y. Kajita · Fujita Health University

R Ogura · Fujita Health University

S. Suga · Fujita Health University

Takehiko Yazaki · Fujita Health University

Takayuki Nakashima ·

Abstract

An encephalitic illness with a fatal outcome occurred in a 9 month old girl with virologically confirmed exanthem subitum. Human herpes-virus-6 (HHV-6) DNA was found in the cerebrospinal fluid at the acute stage of the disease by the polymerase chain reaction, but the virus antigen was not detected in her brain tissue. This suggests that HHV-6-induced encephalitis/encephalopathy may be due to a non-infectious process.

Topics & Keywords

Cytomegalovirus and herpesvirus research Infectious Encephalopathies and Encephalitis Herpesvirus Infections and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Archives of Disease in Childhood

Volume 67, Issue 12, pp. 1484-1485

DOI: 10.1136/adc.67.12.1484

Field-Weighted Citation Impact: 4.69