The Progression of Liver Fibrosis Is Related with Overexpression of the miR-199 and 200 Families

2011280 citationsJournal Articlegold Open Access

Authors

Yoshiki Murakami · Kyoto University

Hidenori Toyoda · Ogaki Municipal Hospital

Masami Tanaka · Tokyo Medical University

Masahiko Kuroda · Tokyo Medical University

Yoshinori Harada · Kyoto Prefectural University of Medicine

Fumihiko Matsuda · Kyoto University

Atsushi Tajima ·

Abstract

Four miRNAs are tightly related to the grade of liver fibrosis in both human and mouse was shown. This information may uncover the critical mechanism of progression of liver fibrosis. miRNA expression profiling has potential for diagnostic and therapeutic applications.

Topics & Keywords

Liver physiology and pathology Liver Disease Diagnosis and Treatment MicroRNA in disease regulation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PLoS ONE

Volume 6, Issue 1, pp. e16081-e16081

DOI: 10.1371/journal.pone.0016081

Field-Weighted Citation Impact: 13.86

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