Septic Shock and Sepsis: A Comparison of Total and Free Plasma Cortisol Levels

2006311 citationsJournal Articlebronze Open Access

Authors

J. T. Ho · South Australia Pathology

Houda S Almusalhi · University of Adelaide

M. John Chapman · Royal Adelaide Hospital

T. Quach · South Australia Pathology

Peter Thomas · Royal Adelaide Hospital

C.J. Bagley · Hanson Institute

John G. Lewis ·

Abstract

Free cortisol is likely to be a better guide to cortisolemia in systemic infection because it corresponds more closely to illness severity. The attenuated cortisol increment after tetracosactrin in RAI is not due to low cortisol-binding proteins. Free cortisol levels can be determined reliably using total cortisol and CBG levels.

Topics & Keywords

Adrenal Hormones and Disorders Hormonal Regulation and Hypertension Vitamin C and Antioxidants Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Clinical Endocrinology & Metabolism

Volume 91, Issue 1, pp. 105-114

DOI: 10.1210/jc.2005-0265

Field-Weighted Citation Impact: 14.29