Lowering cholesterol concentrations and mortality: a quantitative review of primary prevention trials.

1990974 citationsReviewbronze Open Access

Authors

Matthew F. Muldoon · University of Pittsburgh

Stephen B. Manuck · University of Pittsburgh

Karen A. Matthews · University of Pittsburgh

Abstract

The association between reduction of cholesterol concentrations and deaths not related to illness warrants further investigation. Additionally, the failure of cholesterol lowering to affect overall survival justifies a more cautious appraisal of the probable benefits of reducing cholesterol concentrations in the general population.

Topics & Keywords

Cancer, Lipids, and Metabolism Lipoproteins and Cardiovascular Health Diet and metabolism studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMJ

Volume 301, Issue 6747, pp. 309-314

DOI: 10.1136/bmj.301.6747.309

Field-Weighted Citation Impact: 38.29