TRENDS IN POORLY DIFFERENTIATED PROSTATE CANCER 1973 to 1994: OBSERVATIONS FROM THE SURVEILLANCE, EPIDEMIOLOGY AND END RESULTS DATABASE

In the present era ICD-O grade 3 tumors are being detected in increasing number, are less likely to be metastatic at presentation and are more likely to be treated definitively with radical prostatectomy or radiotherapy. Disease specific survival rates observed with radical prostatectomy and radiotherapy in patients with clinically confined tumors support current efforts to detect and treat these highly aggressive tumors while clinically localized.