Enhanced Lipid Peroxidation and Platelet Activation in the Early Phase of Type 1 Diabetes Mellitus

2003140 citationsJournal Article

Authors

Giovanni Davı̀ · University of Palermo

Francesco Chiarelli · University of Palermo

Francesca Santilli · University of Palermo

Mariapina Pomilio · University of Palermo

Sergio Vigneri · University of Palermo

Angela Falco · University of Palermo

Stefania Basili ·

Abstract

These results demonstrate that enhanced lipid peroxidation and platelet activation represent early events in T1DM that are possibly related to an acute inflammatory response. These noninvasive indexes may help in further examining T1DM pathophysiology and monitoring pharmacological interventions to interfere with disease development and progression.

Topics & Keywords

Advanced Glycation End Products research Cardiovascular, Neuropeptides, and Oxidative Stress Research Adipokines, Inflammation, and Metabolic Diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 107, Issue 25, pp. 3199-3203

DOI: 10.1161/01.cir.0000074205.17807.d0

Field-Weighted Citation Impact: 5.74