Multipotent stem/progenitor cells in human biliary tree give rise to hepatocytes, cholangiocytes, and pancreatic islets

2010345 citationsJournal Articlebronze Open Access

Authors

Vincenzo Cardinale · University of North Carolina Health Care

Yunfang Wang · University of North Carolina Health Care

Guido Carpino · Foro Italico University of Rome

Cai-Bin Cui · University of North Carolina Health Care

Manuela Gatto

Massimo Rossi · Sapienza University of Rome

P.B. Berloco · Sapienza University of Rome

Abstract

The phenotypes and availability from all age donors suggest that these stem/progenitors have considerable potential for regenerative therapies of liver, bile duct, and pancreatic diseases including diabetes.

Topics & Keywords

Pancreatic function and diabetes Liver physiology and pathology Genetics and Neurodevelopmental Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Hepatology

Volume 54, Issue 6, pp. 2159-2172

DOI: 10.1002/hep.24590

Field-Weighted Citation Impact: 19.87