Benzyne Click Chemistry: Synthesis of Benzotriazoles from Benzynes and Azides

2008268 citationsJournal Articlegreen Open Access

Authors

Richard C. Larock · Iowa State University

Abstract

A variety of substituted benzotriazoles have been prepared by the [3 + 2] cycloaddition of azides to benzynes. The reaction scope is quite general, affording a rapid and easy entry to substituted, functionalized benzotriazoles under mild conditions.

Topics & Keywords

Click Chemistry and Applications Cyclization and Aryne Chemistry Chemical Synthesis and Analysis

Publication Details

Published in: Organic Letters

Volume 10, Issue 12, pp. 2409-2412

DOI: 10.1021/ol800675u

Field-Weighted Citation Impact: 13.13

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Benzyne Click Chemistry: Synthesis of Benzotriazoles from Benzynes and Azides

Authors

Abstract

Topics & Keywords

Publication Details