Diffusion-weighted MRI hyperintensity patterns differentiate CJD from other rapid dementias

2011388 citationsJournal Articlebronze Open Access

Authors

Paolo Vitali · Fondazione Istituto Neurologico Nazionale Casimiro Mondino

Elio Maccagnano · Fondazione Istituto Neurologico Nazionale Casimiro Mondino

Eduardo Caverzasi · Fondazione Istituto Neurologico Nazionale Casimiro Mondino

Roland G. Henry · Fondazione Istituto Neurologico Nazionale Casimiro Mondino

Aissatou Haman · Fondazione Istituto Neurologico Nazionale Casimiro Mondino

Charles C. Torres-Chae · Fondazione Istituto Neurologico Nazionale Casimiro Mondino

Abstract

The pattern of FLAIR/DWI hyperintensity and restricted diffusion can differentiate sCJD from other RPDs with a high sensitivity and specificity. MRI with DWI and ADC should be included in sCJD diagnostic criteria. New sCJD MRI criteria are proposed.

Topics & Keywords

Prion Diseases and Protein Misfolding Neurological and metabolic disorders Neurological diseases and metabolism

UN Sustainable Development Goals

Quality Education

Publication Details

Published in: Neurology

Volume 76, Issue 20, pp. 1711-1719

DOI: 10.1212/wnl.0b013e31821a4439

Field-Weighted Citation Impact: 13.04