Demyeliating neuropathy and monoclonal IgM antibody to myelin‐associated glycoprotein

1983208 citationsJournal Article

Authors

Geneviève Perruisseau · University of Lausanne

Abstract

We studied a patient with demyelinating neuropathy and monoclonal IgM kappa antibody to the major myelin-associated glycoprotein (MAG). Binding of this monoclonal antibody to the myelin antigen was demonstrated by immunoelectroblot. Binding to MAG seemed to be specific, because it was completely inhibited by MAG isolated from human myelin. Immunostaining was observed with MAG from CNS and peripheral nervous system myelin.

Topics & Keywords

Peripheral Neuropathies and Disorders Monoclonal and Polyclonal Antibodies Research Hereditary Neurological Disorders

Publication Details

Published in: Neurology

Volume 33, Issue 1, pp. 19-19

DOI: 10.1212/wnl.33.1.19

Field-Weighted Citation Impact: 27.59

Command Palette

Demyeliating neuropathy and monoclonal IgM antibody to myelin‐associated glycoprotein

Authors

Abstract

Topics & Keywords

Publication Details