The effects of epinephrine on outcomes of normothermic and therapeutic hypothermic cardiopulmonary resuscitation*

201058 citationsJournal Article

Authors

Shijie Sun · Foundation for the Advancement in Research in Medicine

Wanchun Tang · University of Southern California

Fengqing Song · Society of Critical Care Medicine

Tao Yu · Society of Critical Care Medicine

Giuseppe Ristagno · Mario Negri Institute for Pharmacological Research

Yi Shan · Society of Critical Care Medicine

Yinlun Weng

Abstract

Epinephrine, when administered during normothermic cardiopulmonary resuscitation, significantly increases the severity of postresuscitation myocardial dysfunction and decreases the duration of survival. These detrimental effects of epinephrine, however, no longer exist when it is administered during therapeutic hypothermic cardiopulmonary resuscitation.

Topics & Keywords

Cardiac Arrest and Resuscitation Thermal Regulation in Medicine Respiratory Support and Mechanisms

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Critical Care Medicine

Volume 38, Issue 11, pp. 2175-2180

DOI: 10.1097/ccm.0b013e3181eedad6

Field-Weighted Citation Impact: 6.30