NUPACK: Analysis and design of nucleic acid systems

20101,753 citationsJournal Articlebronze Open Access

Authors

Joseph N. Zadeh · California Institute of Technology

Conrad Steenberg · California Institute of Technology

Justin S. Bois · California Institute of Technology

Brian R. Wolfe · California Institute of Technology

Marshall B. Pierce · California Institute of Technology

Asif R. Khan · California Institute of Technology

Robert M. Dirks

Abstract

sequence design for complexes of nucleic acid strands intended to adopt a target secondary structure at equilibrium.Utilities: evaluation, display, and annotation of equilibrium properties of a complex of nucleic acid strands. NUPACK algorithms are formulated in terms of nucleic acid secondary structure. In most cases, pseudoknots are excluded from the structural ensemble.

Topics & Keywords

Advanced biosensing and bioanalysis techniques DNA and Nucleic Acid Chemistry RNA and protein synthesis mechanisms

Publication Details

Published in: Journal of Computational Chemistry

Volume 32, Issue 1, pp. 170-173

DOI: 10.1002/jcc.21596

Field-Weighted Citation Impact: 12.34

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NUPACK: Analysis and design of nucleic acid systems

Authors

Abstract

Topics & Keywords

Publication Details