Nutritional model of steatohepatitis and metabolic syndrome in the Ossabaw miniature swine #

2009210 citationsJournal Articlebronze Open Access

Authors

Lydia Lee · Indiana University – Purdue University Indianapolis

Mouhamad Alloosh · Indiana University – Purdue University Indianapolis

Romil Saxena · Indiana University School of Medicine

William Van Alstine · Purdue University West Lafayette

Bruce A. Watkins · Purdue University West Lafayette

James E. Klaunig · Indiana University School of Medicine

Michael Sturek

Abstract

Ossabaw pigs fed a modified atherogenic diet develop severe metabolic syndrome and abnormal liver histology with close resemblance to human nonalcoholic steatohepatitis (NASH).

Topics & Keywords

Liver Disease Diagnosis and Treatment Diet, Metabolism, and Disease

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: Hepatology

Volume 50, Issue 1, pp. 56-67

DOI: 10.1002/hep.22904

Field-Weighted Citation Impact: 6.86